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The other two protomers, mVP35c (residues 110172) and mVP35 d (residues 113329), contribute to the majority of the interactions with MARL (Supplementary Data 1)

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Conclusion MDSCs are pivotal mediators of immune evasion in cancer, playing a dual role in both immunosuppressive and non-immunosuppressive tumor-promoting activities, such as supporting cancer stem cell survival, inducing angiogenesis, driving the epithelialmesenchymal transition, and contributing to the formation of pre-metastatic niches