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ACTL6A inhibits ferroptosis of GC cells Because ferroptosis is linked to ROS and GSH regulation, we sought to determine whether ACTL6A inhibits the ferroptosis of GC cells
MRP2, Multi-drug Resistance-associated Protein 2
Xenograft models were conducted to determine the impact of EGR1 overexpression on BC in vivo
Studies have shown significantly reduced GPX3 mRNA levels in chondrocytes from KBD patients, where elevated methylation of CpGs in the GPX3 gene suppresses its transcription, reducing antioxidant function and promoting chondrocyte apoptosis, thus accelerating KBD progression [205,206]
Apolipoprotein E alleledependent antioxidant activity in brains with Alzheimer's disease
At 12mg weekly, trials show 24.2% weight loss at 48 weeks and up to 28.7% at 68 weeks in Phase 3
