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It should be noted that the BBB is a complex interface composed not only by endothelial cells but also by astrocytes and perycites 23, 31 , and these cell types may also influence BBB transport of (poly)phenol metabolites in vivo

This response is often coupled with the selective activation of ATF-4 translation, which mediates a protective response including the upregulation of expression of amino acid transporters and de novo synthesis pathways 35,49

GSH in mitochondria is involved e.g., in the detoxification of reactive oxygen species (ROS

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doi: 10.1007/s11010-011-1217-3 115 MontjeanDMnzoYBenkhalifaMCohenMBellocSCohen-BacriePet al