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The gutbrain axis has been implicated in the pathogenesis of neurological disorders such as multiple sclerosis and Alzheimers disease, as well as acute ischaemic stroke [49]

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Similarly, it has also been found that pancreatic CSE expression and H 2 S production are higher in Zucker diabetic fatty (ZDF) rats than in Zucker fatty and Zucker lean rats (101)

These mechanisms contribute to the aggravation of EAE symptoms in VitB12-restricted animals, shedding light on the involvement of this vitamin in neuroinflammatory conditions generally associated with MS [63]

Interleukin-7 receptor alpha mutational activation can initiate precursor B-cell acute lymphoblastic leukemia