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The FDA cautions that Wegovy carries the risk of such side effects as nausea, diarrhea, constipation, and vomiting

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Although investigational methods such as intranasal or inhaled formulations are still in their initial development phase, they illustrate a widespread initiative to develop alternatives to injection-based treatments

In recent developments, the FDA further expanded semaglutides indication to include reducing the risk of cardiovascular death, heart attack, and stroke in adults with cardiovascular disease who are either obese or overweight

This ties in with point 2

Time from randomization to first occurrence of major adverse cardiovascular event (MACE) was the primary outcome in SUSTAIN-6