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Intracellular free iron is involved in two main pathways of ferroptosis, the nonenzymatic pathway and the enzymatic pathway

Unlike other malignancies, GBM lacks distant metastases, making it an ideal candidate for OV therapy, as the virus remains localized, maximizing its tumor-specific effects

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Furthermore, the treatment of HIV-infected patients with S-adenosylmethionine, a precursor of homocysteine that is used in GSH synthesis, induced an increase of GSH levels in CSF [24]

Table 2 shows a list of main hericenones and erinacines found in H