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The lack of an antitumour effect from the loss of intracellular GSH suggested that extracellular GSH is instead crucial for tumour growth

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In rat and human tissue, high signals for GHSR1a mRNA are found expressed in several hypothalamic nuclei, the pituitary, and the dentate gyrus of the hippocampus, with additional yet reduced signals in CA2 and CA3 of the hippocampus, the substantia nigra, the ventral tegmental area, and the median raphe nuclei (Guan et al., 1997

By boosting levels of glutathione, NAC speeds up the breakdown of acetaminophen

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