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Like KIM-1, expression of CLU is significantly elevated in dedifferentiated tubular cells during AKI but also in polycystic kidney disease, nephrectomy, and renal cell carcinoma (Hidaka et al

Hypersensitivity to levothyroxine, any of its excipients, or similar thyroid preparations

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In diet-induced obese (DIO) mouse models, NNMT inhibition with 5-Amino-1MQ was associated with reduced white adipose tissue mass without affecting food intake, suggesting changes in energy expenditure rather than appetite suppression
Goodsell DS and Olson AJ: Automated docking of substrates to proteins by simulated annealing
