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Progressive pseudogenization: Vitamin C synthesis and its loss in bats

Many people are unable to process and utilize inactive B12

In Japan, the incidence is 10-fold of that in the West, with 17,311 mortalities from BTC in 2007, making it the sixth leading cause of cancer mortality in Japan (5)

Neurol Ther 11 , 14891517 (2022)

Whilst B12 has a low risk of toxicity even at high doses, it is prudent to consider whether such high intake is necessary unless advised by a healthcare professional