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For instance, systemic inflammation driven by microbial products can exacerbate mitochondrial oxidative stress, whereas mitochondrial dysfunctionvia impaired ATP production and release of damage-associated molecular patterns (DAMPs)can itself amplify inflammatory responses and worsen tissue injury (29, 30)

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LVEDP, end diastolic pressure

Antioxidants and atherosclerosis: Dont throw out the baby with the bath water
Darani HY, Sharafi SM
