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In this experiment Schwarzlnder and co-workers (2009) demonstrated a redox perturbation in the mitochondria after Cd exposure with important effects on redox signaling

doi: 10.1097/j.pain.0000000000002857 69 O'MahonySMClarkeGBorreYEDinanTGCryanJF

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NOX2 and nitric oxide synthase use NADPH as a cofactor to produce free radicals [120]

Fipronil, an insecticide that targets gaba receptors, induces neurotoxicity, which may be linked to these selection patterns 66
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