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Some of these areas include the subfornical organ, nucleus of the solitarius tract, nucleus accumbens, hypothalamus, and ventral tegmental area

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[2] In addition to actions at receptors, Semax, as well as a related peptide drug, Selank, have been found to inhibit enzymes involved in the degradation of enkephalins and other endogenous regulatory peptides (IC 50 = 10 M), though the clinical significance of this property is uncertain

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