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This enzyme is entirely dependent on both Folate and Vitamin B12 to perform its job, and the two vitamins execute a precise biochemical dance to make it happen
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However, B12 serum blood levels start dropping, and most of it will be active B12 (holoTC)
(2004) International Meeting for Autism Research (IMFAR)
Importantly, these implications were observed without direct immunosuppression of specific cytokines such as TNF, implying a more regulatory mode of action
