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In the body, androgens are converted to estrogens through the action of aromatase, which is more active in the pulmonary vasculature of patients with PAH

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10.1111/j.1365-201X.2004.01347.x 11 AndersonR

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Apoptosis plays a pivotal role in follicular atresia and follicular depletion, with follicular activation and growth closely associated with cell proliferation and resistance to apoptosis (Krysko et al., 2008)

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