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The copper(II) ion is an essential structural component of GHK-Cu, forming a stable coordination complex through interactions with the Gly-His-Lys tripeptide

Systolic (SBP) and diastolic blood pressure (DBP) were also consistently reduced by incretin-based drugs, ranging from 3.1 and 0.57 mmHg with liraglutide 3.0 mg to 9.2 and 5.1 mmHg with retatrutide, respectively

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