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LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus: from discovery to clinical proof of concept

This distinction helps explain why it progressed into formal obesity trials, whereas the raw fragment itself did not

Lidestri for maintenance of the X-ray laboratory at Columbia University, and W

Carlen PL, Gurevich N, Durand D (1982)

Its development demonstrates how peptide modification can improve upon natural hormones, providing longer duration of action and improved clinical utility

[DOI] [PMC free article] [PubMed] [Google Scholar] 128.Lozoya O.A., Martinez-Reyes I., Wang T., Grenet D., Bushel P., Li J., Chandel N., Woychik R.P., Santos J.H
