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Foster WG, Maharaj-Briceno S, Cyr DG
doi: 10.3389/fimmu.2021.666223

Yes, when taken at recommended doses
Indeed, filamin A has an essential role in intercellular junctions and its mutations influence various signaling pathways involved in valve growth modulation, potentially leading to excessive TGF- and 5-hydroxytryptamine activation, ultimately causing valvular defects (4, 70, 71)

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doi: 10.1016/j.bbadis.2013.04.013
