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Predictions of non-carcinogenic effects are possible when the resulting HQ value is more than 1, but predictions of no adverse health consequences from exposure are obtainable when the determined HQ is equal to or lower than 1

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Notably, these neuroprotective effects were hydrogen-dependent, as silicon dioxide (SiO2) alone showed no comparable activity

In vitro work has used dissociated rat hippocampal neuron cultures for the dendritic-spinogenesis assay