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per oral [99,118,140,142,155,169,170,171,194,203,227,229,233,238,239,241,242,265,266,267,278,279,280,281,282,283,284,285,286]

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Moreover, they have been reported to promote cartilage regeneration in OA and play a role in harmful processes such as osteophyte formation and inflammation, which further exacerbate cartilage degradation (Fig