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The CB2 receptor (CB2R) agonist AM1241, an anti-neuroinflammatory compound, modulates the NLRP3 inflammasome and AMP-activated protein kinase (AMPK) signaling pathways to suppress microglial overactivation, thereby reducing seizure frequency and alleviating depressive-like symptoms (Vayanakkan et al., 2024)

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The World Anti-Doping Agency (WADA) classified BPC-157 as a prohibited substance under the S0 category (non-approved substances) in 2022

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