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1,6 (2012): e003152

The impact of curcumin on arterial stiffness has also been investigated clinically and preclinically, with somewhat limited doseresponse data

Ligation of Toll-like receptors (TLRs) on intestinal epithelial cells by bacterial products promotes epithelial cell proliferation, secretion of IgA into the gut lumen and expression of antimicrobial peptides

A., Goodyear L

Finally, we discuss the current data about the feasibility of increasing GSH levels, which could be used to prevent and subdue the disease

Possible future directions in preclinical and clinical research and issues involving large-scale manufacturing and deployment are discussed, including combinatorial approaches using immune checkpoint inhibitors