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The protein owes its name to its simultaneous localisation in both synaptic vesicle as well as nuclear envelope in a type of stingray (Clayton and George, 1998)

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Unlike Th cells and CTLs, which are known for their antitumor immune roles, Tregs, distinguished by elevated Foxp3 expression, are crucial for suppressing antitumor immune reactions [84]

This explains the different side effect profiles

Watch for: Tingling or numbness in the arm, hand, or fingers Muscle weakness or difficulty moving the arm Shoulder pain or a deep, aching sensation Swelling or inflammation at the injection site Loss of grip strength or coordination in the hand Pain that radiates from the shoulder down to the hand If your arm numbness lasts more than a few weeks, worsens, or affects daily life, you may be dealing with a more serious vaccine-related nerve injury

These pathways affect collagen remodeling, tissue regeneration, and other cellular signals involved in healing