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Description
Carbon 228 , 9 (2024)

Lancet Infect Dis (2018) 18:137784

Mutations in CFTR, which form the basis for the clinical manifestations of cystic fibrosis, affect the epithelial innate immune function in the lung, resulting in exaggerated and ineffective airway inflammation that fails to eradicate pulmonary pathogens

The kinetic parameters were determined in the presence of varying concentrations of tyrosine and DOPA from 0.1 to 5.5 mM and calculated by non-linear curve fitting using Origin8.0

doi: 10.1080/10942912.2020.1814324 11

When interpreted together with the findings of the STEP 4 withdrawal trial and STEP 1 off-treatment extension study, which both showed weight regain after semaglutide discontinuation (after 20 weeks treatment in STEP 4 and 68 weeks treatment in STEP 1) 23,24 , these results support the benefit of continued semaglutide treatment for sustained weight loss
