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This suggests that the decoupling observed in P301L SH-SY5Y cells may be linked to the overexpression of P301Ltau

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Artificial disc prosthesis for the treatment of degenerative intervertebral disc mainly aims at restoring the mechanical properties of the IVD (such as the height of intervertebral space and local mobility of spine) and also raises requirements for biological properties (such as promoting the growth and differentiation of IVD cells)

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Another potential mediator is the imbalance of endogenous anabolic hormones (e.g., testosterone, insulin-like growth factor 1) and catabolic factors, such as glucocorticoids and myostatin [9, 11]

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Compared with Hb H 2 O 2 decomposition in a dose-dependent manner, KDS12025 decreased Hb EC 50 for H 2 O 2 decomposition by 4.7-fold and EC 20 by 98-fold (Fig

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