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Consistent with this notion, MCT9 expression is enhanced by tumor necrosis factor- (TNF- )

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Recent neuroimaging and neurophysiological studies indicate that the motor cortex (CRTX) is both structurally and functionally affected in SMA patients, with variations in cortical changes correlating with disease severity and phenotype, suggesting the coexistence of compensatory and maladaptive plasticity alongside neurodegeneration

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