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That alone is remarkable, but Commander players have found ways to make this life drain effect even stronger in Commander, such as in white-black decks

Chrome Mox Zuran Orb Brainstorm Sensei's Divining Top Mystical Tutor Spell Pierce Swords to Plowshares Fire/Ice Lightening Helix Snapcaster Mage Balance Isochron Scepter Remand Arcane Denial Lat-Nam's Legacy Disenchant Trinket Mage Timetwister Jace, the Mind Sculptor Elspeth, Knight Errant Gideon Jura Temporal Mastery Terminus Bonfire of the Damned 16 Lands (I cannot be bothered to work out a sensible mana base for a deck I'm not going to battle with, sorry

Pick the bosses and signature cards you actually want

You can't flip them in Shiko decks, if you are making token copies of them, but I think getting their ETB abilities when they come into play is enough value

Here are my favorites

Wizards initially pushed Nadu for Commander and ended up breaking Modernand Commander, for that matter