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Once-Weekly Semaglutide in Persons with Obesity and Knee Osteoarthritis

The 15mg dose in SURMOUNT-1 produced the 22.5% average body weight reduction, but this was measured at week 72, so the full effect takes time

This treatment is most effective when combined with a healthy lifestyle and regular follow-up

The reactions range from a mild pink circle that fades in hours to angry welts that spread across the abdomen over days, causing burning, itching, and genuine discomfort

It typically affects one eye but can occur in both
