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Description
Impact of body weight dynamics following intentional weight loss on fracture risk: results from the action for health in diabetes study

Key findings: Prescribing trends Using a subset of Truveta Data, Truveta Research identified people who were prescribed a GLP-1 RA between January 01, 2019 and December 31, 2025

Mazzolai L, Teixido-Tura G, Lanzi S, et al

It also activates p38 MARK, ERK1/2 cascade, and JNK cascade, which promotes apoptosis and inflammation (Potilinski et al., 2020)

Overall, these results demonstrate that GLP-1 RAs may exert their therapeutic effects through multiple mechanisms in MASH treatment

[DOI] [PMC free article] [PubMed] [Google Scholar] 77.Sinnathurai P., Lau W., Vieira de Ribeiro A.J., Bachovchin W.W., Englert H., Howe G., Spencer D., Manolios N., Gorrell M.D
