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Against this backdrop of investor exuberance, 2024 also delivered a dose of realism to temper runaway excitement about many novel AOM assets purported best-in-class profile, often based on nothing more than limited topline data from phase 1 trials

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The scale moved

Pfizer emphasized that across its safety database of 1,400+ patients, liver enzyme elevations generally matched rates seen with approved GLP-1 medications

Bakbak E, Terenzi DC, Trac JZ, Teoh H, Quan A, Glazer SA, et al