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Overall, the evidence suggests that the opposing effects of ghrelin and GLP-1 on mediating GI-associated malaise may be a driving component of their opposing effects on food reward-motivated behaviors

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Man spricht hier von der Halbwertszeit, die bei GLP-1 vergleichsweise kurz ist
doi: 10.1038/s42255-023-00966-w 75 NrregaardPKDeryabinaMATofteng SheltonPFogJUDaugaardJRErikssonPOet al
When we eat, food travels through the mouth, throat, esophagus, and stomach before ending up in the small intestine

How semaglutide interacts with your blood Understanding the biological mechanisms helps explain why the evidence points in two directions simultaneously