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5 Like any medicine, GLP-1s have potential side effects

The FDA initiated an investigation into Victozas potential link to pancreatic cancer in 2013 after safety concerns emerged, and Victoza has been associated with an increased risk of pancreatic cancer in some studies and adverse event reporting, prompting continued evaluation

[DOI] [PMC free article] [PubMed] [Google Scholar] 50.Zhou L., Qu H., Yang L., Shou L

The optimal timeframe involves balancing the enhanced response from later initiation with the need to avoid WR, considering the complex interplay between the timing of GLP1-RAs initiation and its impact on WL and WR post-surgery

There is also a simpler explanation

If you're also dealing with muscle aches or joint pain on Zepbound, those symptoms cluster with the same dose-escalation windows and respond to similar timing strategies