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In Covid-19, ED (a hallmark of the disease) and activation of adhesion molecules trigger the progression of immunothrombosis and the development of critical complications (Bonaventura et al

In those cases, medications like Ozempic and other GLP-1s may also be needed

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is supported by a Banting and Best Diabetes Centre Novo Nordisk Chair in Incretin biology and a Sinai Health Novo Nordisk Foundation Fund in Regulatory Peptides as well as Canadian Institute for Health Research (CIHR) grant 192044

Tirzepatide (Mounjaro, Zepbound) averages roughly 2022.5% body-weight loss versus about 15% for semaglutide (Wegovy) and 1014% for Ozempic (SURMOUNT/STEP trial data)
In addition, in mice with bleomycin-induced pulmonary fibrosis, liraglutide treatment inhibited infiltration of immune cells and decreased the content of TGF- 1
