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Interrogating brain tissue at the proteomic level may therefore oversimplify a complex picture, neglecting subtle alterations within the peptidome

L., & Chung, J

The Lancet Child & Adolescent Health , 3 (11), 759761

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14, 23, 24, 25, 26 In preclinical studies, excess oxidative stress is consistently observed in the brains of animal models with etiological triggers relevant to mental illness, in particular SZ

These results suggest the OS-induced initial impairment of a few glycolytic processes in the early stages of the disease and the subsequent widespread alteration of most of the glycolytic pathway in the late stage