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Description
GSK3B is a constitutively active protein kinase that acts as a negative regulator for transcription factors, microtubules, Wnt signalling, as well as in the hormonal control of glucose homeostasis 39,40

Graphical abstract Neurons derived from human induced pluripotent stem cells (hiPSCs) of patients carrying mutations in CHMP2B (FTD3) display major metabolic alterations compared to CRISPR/Cas9 generated isogenic controls

doi: 10.1016/j.cbi.2017.04.024 82 ZhuXBNiuZHFanWMChengMYChenQZhangAJ
Cytosolic Ca2+ regulates the energization of isolated brain mitochondria by formation of pyruvate through the malate-aspartate shuttle

We discuss further literature from the perspective of therapeutic measures in iron metabolic kinetics

LuPTakiguchiSHondaYLuYMitsuiTKatoSet al
