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Description
This explains one of the most common frustrations with GLP-1 therapy

They are distinguished by their capability to produce elevated levels of pro-inflammatory cytokines, including IL-1, IL-6 and TNF- [79]
Neuropsychopharmacology, 45, 1207-1214

Nikeghbalian S, Bananzadeh A, Yarmohammadi H
Oral formulations are also emerging

But it would seem to make sense to continue the patent - if thats the real price
