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Nakade, Y., Tsukamoto, K., Iwa, M., Pappas, T

Morroniside, a GLP-1R agonist, reduced mechanical allodynia and thermal hyperalgesia in a dose-dependent manner in a rat model of neuropathic pain, with peak effects within 1 h and lasting over 4 h [38]

7678 These modulators bind regions of the receptor distinct from GLP-1(736)amide, and they might cause GLP-1(736)amide to adopt a conformation that biases its signal transduction properties so that it activates select downstream pathways

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This versatility makes it particularly valuable for laboratories running simultaneous protocols involving different research peptides

[DOI] [PubMed] [Google Scholar] 49.Frost G, Sleeth ML, Sahuri-Arisoylu M, et al
