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Lactic acidosis: Though rare, Metformin can cause a dangerous condition called lactic acidosis, which requires immediate medical attention

Retatrutide is investigational with no FDA-approved dosing protocol, so any split approach should be discussed with a supervising healthcare provider first

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How They Work: Mechanism of Action Phentermine: Stimulating the Nervous System Phentermine works by stimulating the central nervous system, causing the release of norepinephrine, which helps suppress appetite

Wegovy can make low blood sugar more likely if you also use insulin or a sulfonylurea