muscle loss with glp 1 and GLP-1R agonists use Recent JAMA Article on Muscle

However, precise analysis of the relationship between the cost of paying for GLP-1s and the return on investmentcost savings due to increased productivity and reduced health care utilizationmay become challenging as, in the United States, there are few mechanisms and incentives to produce these data and analyze them over the long term, Persad noted

Those questions matter because long-term success is about more than body weight

[Google Scholar] 57.Almandoz J.P., Wadden T.A., Tewksbury C., Apovian C.M., Fitch A., Ard J.D., Li Z., Richards J., Butsch W.S., Jouravskaya I., et al

Wang B, Zhong J, Lin H, et al

Theres a great risk of muscle loss and malnutrition They can interfere with the absorption of other meds, including psychiatric meds Some people wont lose any weight at all Most people will regain weight after they discontinue use (as is the case with any diet) Theres limited long term research and a whole bunch of misinformation They can alter taste perception and decrease the enjoyment of eating So we know they can help with diabetes, theres a long list of risks and more we dont know, and at the same time some people have found GLP-1s offer the potential to re-connect with internal signals and eventually help build body trust

The compounding effect of sustained caloric reduction produces significant body composition changes