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Methods Data source Managed by the FDA, FAERS compiles AE reports from various contributors such as healthcare professionals, patients, drug manufacturers, and more [Reference Anand, Ensor, Trachtenberg and Bernicker10Reference Yang, Lv, Yu, Mei, Xiang and Zhao12]

Moreover, no medicinal product bearing the name "GLP-1" is authorised

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Phentermine has been used for short-term weight management (typically 12 weeks or less) since 1959, while GLP-1 agonists like Ozempic and Mounjaro gained obesity indication approval only in 2021 and 2023 respectively, backed by multi-year trial data

In recent years, GLP-1 receptor agonistsdrugs like Ozempic and Wegovyhave exploded in popularity as effective tools for rapid weight loss

Well-designed clinical trials are needed to clarify the therapeutic potential of GLP-1RAs in ALS [44,45]
