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It also contributes to other health problems such as cardiovascular diseases, insulin resistance, diabetes or cancers risk [34, 35]

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Whether genetic or metabolic stratification identifies a subgroup that benefits

The first two have been reported to be co-expressed with GLP-1 in the small and large intestine respectively, with Neurotensin being reported also in pancreatic -cells (210), while Xenin in a sub population of duodenal GIP positive cells and -cells

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All participants provided written informed consent, according to the ICH GCP and regulatory and legal requirements of the participating countries
