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Tirzepatide produced greater A1c reductions than semaglutide in the SURPASS-2 head-to-head trial, making it the stronger option for glycemic control

For more on this topic, see our guide on why tirzepatide might not be working

Experienced an issue in the beginning

For people experiencing weight gain while still on tirzepatide, these numbers actually provide reassurance

The lifestyle interventions should be monitored, adapted, and perpetuated in an informed consent with the patient over the years, regardless of whether additional medical or surgical therapy is started in the course of T2D or obesity ( Incretin-based therapies Incretins are hormones that are secreted from enteroendocrine cells in the gut mucosa after a meal

Always stay at each dose for at least 4 weeks