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Description
Despite a dearth of comprehensive evidence for numerous pharmacological interventions, healthcare providers have turned to symptomatic treatments to mitigate a spectrum of issues, including psychological distress like anxiety and depression, emotional volatility (pseudobulbar affect), involuntary muscle twitches, pervasive fatigue, sleep disturbances, and a range of physical discomforts from muscle cramps and spasms to immobility-induced musculoskeletal pain, neuropathic pain, sialorrhea, spasticity, constipation, and urinary urgencies

[DOI] [PMC free article] [PubMed] [Google Scholar] 55.Laborde E

59 Citrus

A range of studies has revealed links between metabolic enzymes and the cytoskeleton 21,22,23 , which adapt metabolic pathways to cellular needs
doi: 10.1097/PSY.0000000000000537

Englewood Cliffs: Prentice-Hall, Inc
