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It is a two-part trial
Co-treatment of 4d (A2-thio-imidazole derivative), a novel TGR5 agonist, and Sitagliptin (DPP-4 inhibitor) exhibited a GLP-1 secretion and glucose-lowering effect in animal models, while this compound alone exhibits only a slight 1.3-fold increase in GLP-1 secretion [182]
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[DOI] [PMC free article] [PubMed] [Google Scholar] 31.Shao S., Xu Q., Yu X., Pan R., Chen Y
