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Mitochondrial oxidative stress and respiratory dysfunctions in cancer cells may, therefore, lead to the activation of apoptotic signals by the release of apoptosis-inducing factors and proteins and subsequent activation of the caspases [17], [18], [19]

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Skin lightening and skin whitening are terms that are often used interchangeably, but they can refer to slightly different concepts

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doi: 10.1016/j.jhep.2008.10.020