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Ozempic and Wegovy are both based on semaglutide, with Wegovy specifically designed for weight loss, and Mounjaro is a newer option that combines tirzepatide for effective weight management

Evidence from dual-energy X-ray absorptiometry and MRI sub-studies suggests that 2545% of total weight loss with semaglutide and tirzepatide may come from reductions in lean body mass

That keeps things fast and cheap, but it puts more on you

Protein: The Unsung Hero Due to the rapid pace of weight loss GLP-1s are known for, losing muscle can be a side effect

Frequently reported side effects include: Nausea Vomiting Diarrhea Constipation Stomach pain Reduced appetite Indigestion These symptoms are generally linked to the way GLP-1 drugs affect digestion and appetite regulation

Then, the researchers administered exendin-4 via intrathecal injection to the experimental rats and observed a reduction in pain sensitivity, alleviation of neural inflammation, and suppression of inflammatory factors such as IL-1, TNF-, and iNOS