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The non-randomized trial by Pettegrew et al 12 assessed with ROBINS-I, showed a critical risk of bias from confounding and serious risk from participant selection, although other domains were low risk

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(PubMed) De Grandis D, Minardi C

A fine balance of AMPK activity is necessary to increase basal autophagy activity and maintain neuronal and endothelial cell survival during periods of metabolic homeostasis loss (230, 234, 575, 584)

Organic mercury compounds are toxic and excessive exposure can cause brain and kidney damage

Axonal excitability studies also support a mixed pathology comprising features of axonal degeneration and regeneration [121]