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The insurer was paying $1,000 or more per month for medications that the majority of recipients would abandon within months, often without achieving the weight loss or metabolic improvements that justified the expense in the first place

Lyu X, Zhu X, Zhao B, et al

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The demographic distribution of those most likely to stop treatment was as follows: patients of color, men, people enrolled in Medicare or Medicaid, those living in areas with very high social needs, heart failure, obesity or other cardiovascular diseases prior to drug initiation, and those experiencing new gastrointestinal adverse effects at follow-up [132]

Current understanding of dysbiosis in disease in human and animal models

One article outlined 25-30% of a 1600 kcal diet, which works out to 100-120 g/day of nutritional protein (Sievenpiper et al 2026)
