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[DOI] [PMC free article] [PubMed] [Google Scholar] 45.Jeon J.Y., Choi S.E., Ha E.S., Lee H.B., Kim T.H., Han S.J., Kim H.J., Kim D.J., Kang Y., Lee K.W

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When RANK on the surface of osteoclast precursor cells binds with RANKL released by osteoblasts, the expression of osteoclast-related genes in the nucleus increases through the NF-B and calmodulin/nuclear factor of activated T-cell (CN/NFATc1) pathways, which ultimately results in the activation of osteoclast-related genes in the osteoclast precursor cells and thus promotes osteoclastic differentiation

But for some reason I still like it and will continue to try it for a few more months before quitting