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The gut-brain axis: These drugs interact with the area postrema in the brainstem (the region that controls the vomiting reflex) to reduce appetite, which can sometimes trigger nausea
In addition, CBD increased the levels of protein expression of CPT1, ACSL, SIRT1, and PLIN, while regulating JNK2, SREBP1, and LPL
Unlike semaglutide (Ozempic/Wegovy) or tirzepatide (Mounjaro/Zepbound), retatrutide activates the glucagon receptor, which promotes the breakdown of glycogen the body's stored carbohydrate

10.1007/s13300-024-01566-x
J Pediatr Surg 35:847851
doi: 10.1210/jc.2018-01010
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