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Circulation 149 , 450462
A dual agonist for GLP-1R and glucose-dependent insulinotropic polypeptide receptor (GIPR), discussed later, may attenuate these side effects through GIP receptor signaling

Exp Neurobiol (2017) 26:22739

Inhibiting PFKFB3 attenuates TGF-1 + IL-1-stimulated NLRP3 inflammasome activation and fibroblast activation The effects of PFKFB3-driven glycolysis on NLRP3 inflammasome activation in fibroblasts under the stress of TGF-1 + IL-1 were investigated by using 3PO, a selective PFKFB3 inhibitor
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Lamont BJ, Li Y, Kwan E, Brown TJ, Gaisano H, and Drucker DJ